{"id":1730,"date":"2024-01-24T10:44:12","date_gmt":"2024-01-24T10:44:12","guid":{"rendered":"https:\/\/www.ahb-lab.com\/?p=1730"},"modified":"2024-01-24T10:46:04","modified_gmt":"2024-01-24T10:46:04","slug":"exploring-peptide-yy-balancing-hunger-and-gut-immunity","status":"publish","type":"post","link":"https:\/\/www.ahb-lab.com\/zh\/news\/exploring-peptide-yy-balancing-hunger-and-gut-immunity\/","title":{"rendered":"\u63a2\u7d22\u80bd YY\uff1a\u5e73\u8861\u9965\u997f\u548c\u80a0\u9053\u514d\u75ab\u529b"},"content":{"rendered":"<p>\u80bd YY\uff08PYY\uff09\u662f\u4e00\u79cd <a href=\"https:\/\/www.yourhormones.info\/hormones\/peptide-yy\/\">\u6fc0\u7d20<\/a> PYY\u4f20\u7edf\u4e0a\u56e0\u5176\u5728\u98df\u6b32\u8c03\u8282\u4e2d\u7684\u4f5c\u7528\u800c\u95fb\u540d\uff0c\u4f46\u6700\u8fd1\u5374\u6210\u4e3a\u7ef4\u6301\u80a0\u9053\u5065\u5eb7\u548c\u514d\u75ab\u529b\u7684\u5173\u952e\u89d2\u8272\u3002\u829d\u52a0\u54e5\u5927\u5b66\u7684\u7814\u7a76\u63ed\u793a\u4e86PYY\u7684\u591a\u65b9\u9762\u529f\u80fd\uff0c\u62d3\u5c55\u4e86\u6211\u4eec\u5bf9\u80a0\u9053\u5065\u5eb7\u548c\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u7684\u8ba4\u8bc6\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u4e86\u89e3\u80bd YY\uff1a\u4e0d\u4ec5\u4ec5\u662f\u98df\u6b32\u6fc0\u7d20<\/h2>\n<p>\u80bd YY \u7531\u80a0\u9053\u5185\u5206\u6ccc\u7ec6\u80de\u4ea7\u751f\uff0c\u662f\u4f17\u6240\u5468\u77e5\u7684\u9971\u8179\u611f\u8c03\u8282\u5242\u3002\u5f53\u6444\u5165\u8db3\u591f\u7684\u98df\u7269\u65f6\uff0c\u8fd9\u79cd\u6fc0\u7d20\u5c31\u4f1a\u5411\u8eab\u4f53\u53d1\u51fa\u4fe1\u53f7\uff0c\u5728\u98df\u6b32\u7ba1\u7406\u4e2d\u53d1\u6325\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002\u7136\u800c\uff0c\u6700\u65b0\u7814\u7a76\u63ed\u793a\u4e86PYY\u7684\u53e6\u4e00\u4e2a\u91cd\u8981\u529f\u80fd--\u5b83\u662f\u4e00\u79cd\u6297\u83cc\u80bd\uff0c\u7279\u522b\u662f\u5728\u5e73\u8861\u54fa\u4e73\u52a8\u7269\u80a0\u9053\u771f\u83cc\u65b9\u9762\u7684\u4f5c\u7528\u3002<\/p>\n<h3>\u80bd YY \u5728\u514d\u75ab\u8c03\u8282\u4e2d\u7684\u4f5c\u7528<\/h3>\n<p>\u829d\u52a0\u54e5\u5927\u5b66\u7684\u8d44\u6df1\u4f5c\u8005\u3001\u533b\u5b66\u535a\u58eb Eugene B. Chang \u5f3a\u8c03\u4e86\u8fd9\u4e00\u53d1\u73b0\u7684\u91cd\u8981\u610f\u4e49\u3002\u4ee5\u524d\uff0c\u6211\u4eec\u5bf9\u5fae\u751f\u7269\u7fa4\u4e2d\u771f\u83cc\u7684\u8c03\u63a7\u8fd8\u4e0d\u662f\u5f88\u4e86\u89e3\u3002\u73b0\u5728\u5f88\u6e05\u695a\u4e86\uff0cPYY \u5bf9\u7ef4\u6301\u5065\u5eb7\u7684\u771f\u83cc\u5e73\u8861\u81f3\u5173\u91cd\u8981\uff0c\u5b83\u80fd\u786e\u4fdd\u8fd9\u4e9b\u5fae\u751f\u7269\u4fdd\u6301\u5171\u751f\u72b6\u6001\uff0c\u5bf9\u80a0\u9053\u65e0\u5bb3\u3002<\/p>\n<p>PYY\u7684\u5176\u4ed6\u529f\u80fd\u662f\u7531\u7ea6\u745f\u592b-\u76ae\u57c3\u5c14\uff08Joseph Pierre\uff09\u535a\u58eb\u5728\u5f20\u7684\u5b9e\u9a8c\u5ba4\u5de5\u4f5c\u671f\u95f4\u53d1\u73b0\u7684\u3002\u76ae\u57c3\u5c14\u6700\u521d\u5173\u6ce8\u7684\u662fPYY\u7684\u98df\u6b32\u8c03\u8282\u529f\u80fd\uff0c\u540e\u6765\u4ed6\u53d1\u73b0\u4e86PYY\u7684\u6297\u771f\u83cc\u7279\u6027\uff0c\u5c24\u5176\u662f\u6297\u767d\u8272\u5ff5\u73e0\u83cc\uff08\u4e00\u79cd\u5e38\u89c1\u7684\u80a0\u9053\u771f\u83cc\uff09\u7684\u7279\u6027\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u80bd YY \u7684\u6297\u771f\u83cc\u7279\u6027\u4e0e\u80a0\u9053\u5065\u5eb7<\/h2>\n<p>\u5728\u6b63\u5e38\u60c5\u51b5\u4e0b\uff0c\u767d\u8272\u5ff5\u73e0\u83cc\u4ee5\u65e0\u5bb3\u7684\u9175\u6bcd\u72b6\u6001\u5b58\u5728\u4e8e\u80a0\u9053\u4e2d\u3002\u7136\u800c\uff0c\u5b83\u53ef\u4ee5\u8f6c\u5316\u4e3a\u6bd2\u6027\u66f4\u5f3a\u7684\u5f62\u5f0f\uff0c\u5f62\u6210\u751f\u7269\u819c\uff0c\u5bfc\u81f4\u9e45\u53e3\u75ae\u7b49\u611f\u67d3\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u7531\u5c0f\u80a0\u4e2d\u7684\u5e15\u5948\u65af\u7ec6\u80de\u8868\u8fbe\u7684\u4e00\u79cdPYY\u53d8\u4f53\u80fd\u963b\u6b62\u8fd9\u79cd\u8f6c\u5316\uff0c\u4ece\u800c\u5c55\u793a\u4e86PYY\u5728\u62b5\u5fa1\u6709\u5bb3\u771f\u83cc\u53d8\u5316\u65b9\u9762\u7684\u5173\u952e\u4f5c\u7528\u3002<\/p>\n<h3>\u5bf9\u6d88\u5316\u7cfb\u7edf\u75be\u75c5\u7684\u5f71\u54cd<\/h3>\n<p>\u8fd9\u4e00\u53d1\u73b0\u4e0e\u514b\u7f57\u6069\u75c5\u7b49\u6d88\u5316\u7cfb\u7edf\u75be\u75c5\u60a3\u8005\u5c24\u5176\u76f8\u5173\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u60a3\u8005\u7684Paneth\u7ec6\u80de\u901a\u5e38\u529f\u80fd\u5f02\u5e38\u3002\u7531\u4e8ePYY\u6c34\u5e73\u7684\u6539\u53d8\uff0c\u8fd9\u79cd\u529f\u80fd\u969c\u788d\u53ef\u80fd\u4f1a\u5f71\u54cd\u80a0\u9053\u771f\u83cc\u7684\u5e73\u8861\uff0c\u4e3a\u8fd9\u7c7b\u75be\u75c5\u63d0\u4f9b\u4e86\u6f5c\u5728\u7684\u65b0\u6cbb\u7597\u9776\u70b9\u3002<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-1732\" src=\"https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x.png\" alt=\"Diet. Slimming. Obesity.\" width=\"1580\" height=\"726\" srcset=\"https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x.png 1580w, https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x-300x138.png 300w, https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x-1024x471.png 1024w, https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x-768x353.png 768w, https:\/\/www.ahb-lab.com\/wp-content\/uploads\/2024\/01\/WX20240124-183718@2x-1536x706.png 1536w\" sizes=\"(max-width: 1580px) 100vw, 1580px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h2>\u591a\u80bd YY \u7684\u53cc\u91cd\u529f\u80fd<\/h2>\n<p>\u80bd YY \u901a\u5e38\u7f29\u5199\u4e3aPYY\uff0c\u662f\u4e00\u79cd\u975e\u51e1\u7684\u751f\u7269\u5206\u5b50\uff0c\u5c55\u793a\u4e86\u5927\u81ea\u7136\u5728\u529f\u80fd\u591a\u6837\u6027\u65b9\u9762\u7684\u72ec\u521b\u6027\u3002\u8fd9\u79cd\u6fc0\u7d20\u7531 36 \u4e2a\u6c28\u57fa\u9178\u94fe\u7ec4\u6210\uff0c\u6839\u636e\u5176\u5728\u4f53\u5185\u7684\u751f\u6210\u90e8\u4f4d\u4e0d\u540c\uff0c\u5177\u6709\u72ec\u7279\u7684\u53cc\u91cd\u529f\u80fd\u3002\u5f53PYY\u7531Paneth\u7ec6\u80de\uff08\u80a0\u9053\u5185\u58c1\u7684\u7279\u5316\u7ec6\u80de\uff09\u5206\u6ccc\u65f6\uff0c\u5b83\u5728\u7ef4\u6301\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u5e73\u8861\u65b9\u9762\u53d1\u6325\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002\u5728\u8fd9\u91cc\uff0c\u5b83\u5145\u5f53\u4e86\u6297\u771f\u83cc\u80bd\u7684\u89d2\u8272\uff0c\u5bf9\u4e8e\u6291\u5236\u6709\u5bb3\u771f\u83cc\u7684\u8fc7\u5ea6\u751f\u957f\u548c\u786e\u4fdd\u5065\u5eb7\u7684\u80a0\u9053\u73af\u5883\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u80c3\u80a0\u9053\u5185\u5206\u6ccc\u7ec6\u80de\u4ea7\u751f\u7684PYY\u5f62\u5f0f\u7565\u6709\u4e0d\u540c\u3002\u8fd9\u79cd\u53d8\u4f53\u662f\u4e00\u79cd\u91cd\u8981\u7684\u9971\u8179\u611f\u6fc0\u7d20\uff0c\u662f\u4eba\u4f53\u98df\u6b32\u8c03\u8282\u7cfb\u7edf\u4e0d\u53ef\u6216\u7f3a\u7684\u7ec4\u6210\u90e8\u5206\u3002\u5b83\u5411\u5927\u8111\u53d1\u51fa\u4fe1\u53f7\uff0c\u8868\u660e\u4eba\u4f53\u5df2\u7ecf\u6444\u5165\u4e86\u8db3\u591f\u7684\u98df\u7269\uff0c\u4ece\u800c\u5e2e\u52a9\u8c03\u8282\u98df\u7269\u6444\u5165\u91cf\uff0c\u9632\u6b62\u66b4\u996e\u66b4\u98df\u3002PYY\u7684\u8fd9\u4e00\u7279\u6027\u5bf9\u4e86\u89e3\u548c\u6cbb\u7597\u4e0e\u98df\u6b32\u6709\u5173\u7684\u75be\u75c5\uff08\u5982\u80a5\u80d6\u75c7\u548c\u996e\u98df\u5931\u8c03\u75c7\uff09\u5177\u6709\u91cd\u8981\u610f\u4e49\uff0c\u56e0\u6b64\u7279\u522b\u5f15\u4eba\u5173\u6ce8\u3002<\/p>\n<p>\u6b64\u5916\uff0cPYY \u7684\u53cc\u91cd\u529f\u80fd\u751f\u52a8\u5730\u8bf4\u660e\u4e86\u751f\u7269\u5206\u5b50\u7684\u9002\u5e94\u6027\u548c\u590d\u6742\u6027\u3002\u5b83\u53cd\u6620\u4e86\u4e00\u79cd\u8fdb\u5316\u6548\u7387\uff0c\u5373\u5355\u4e2a\u5206\u5b50\u53ef\u4ee5\u5728\u751f\u7269\u4f53\u5185\u626e\u6f14\u591a\u79cd\u4e0d\u540c\u7684\u89d2\u8272\uff0c\u9002\u5e94\u4e0d\u540c\u7684\u751f\u7406\u73af\u5883\uff0c\u53d1\u6325\u91cd\u8981\u529f\u80fd\u3002<\/p>\n<h3>\u672a\u6765\u7814\u7a76\u548c\u6f5c\u5728\u7597\u6cd5<\/h3>\n<p>\u6700\u8fd1\u5728\u4e86\u89e3\u591a\u80bd YY \u7684\u4f5c\u7528\u548c\u673a\u5236\u65b9\u9762\u53d6\u5f97\u7684\u8fdb\u5c55\u5f97\u5230\u4e86\u4e3b\u8981\u533b\u7597\u548c\u7814\u7a76\u673a\u6784\u7684\u5927\u529b\u652f\u6301\u3002\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08National Institutes of Health\uff09\u3001\u80af\u5c3c\u65af-\u96f7\u5b81\u57fa\u91d1\u4f1a\uff08Kenneth Rainin Foundation\uff09\u548c\u829d\u52a0\u54e5\u5927\u5b66\u80c3\u80a0\u9053\u7814\u7a76\u57fa\u91d1\u4f1a\uff08University of Chicago Gastrointestinal Research Foundation\uff09\u90fd\u5728\u8d44\u52a9\u548c\u4fc3\u8fdb\u8fd9\u9879\u7a81\u7834\u6027\u7814\u7a76\u65b9\u9762\u53d1\u6325\u4e86\u5173\u952e\u4f5c\u7528\u3002<\/p>\n<p>\u8fd9\u9879\u5bf9PYY\u7684\u5168\u9762\u7814\u7a76\u4e0d\u4ec5\u52a0\u6df1\u4e86\u6211\u4eec\u5bf9\u80a0\u9053\u6fc0\u7d20\u7684\u4e86\u89e3\uff0c\u8fd8\u4e3a\u533b\u5b66\u7814\u7a76\u548c\u6f5c\u5728\u6cbb\u7597\u5e94\u7528\u5f00\u8f9f\u4e86\u65b0\u9014\u5f84\u3002PYY\u5728\u80a0\u9053\u5065\u5eb7\u548c\u98df\u6b32\u8c03\u8282\u65b9\u9762\u7684\u53cc\u91cd\u4f5c\u7528\u4f7f\u5176\u6210\u4e3a\u5f00\u53d1\u6cbb\u7597\u5404\u79cd\u5065\u5eb7\u95ee\u9898\u7684\u6f5c\u5728\u9776\u70b9\u3002\u4f8b\u5982\uff0cPYY \u5728\u8c03\u8282\u98df\u6b32\u65b9\u9762\u7684\u4f5c\u7528\u4e3a\u91c7\u7528\u65b0\u65b9\u6cd5\u6cbb\u7597\u80a5\u80d6\u75c7\u548c\u76f8\u5173\u4ee3\u8c22\u75be\u75c5\u63d0\u4f9b\u4e86\u673a\u4f1a\u3002\u540c\u6837\uff0c\u5b83\u5728\u7ef4\u6301\u80a0\u9053\u5065\u5eb7\u65b9\u9762\u7684\u529f\u80fd\u4e5f\u80fd\u4e3a\u80a0\u9053\u75be\u75c5\u548c\u5fae\u751f\u7269\u7fa4\u7d0a\u4e71\u7684\u75be\u75c5\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u5bf9PYY\u529f\u80fd\u7684\u63a2\u7d22\u53ef\u80fd\u4f1a\u5bf9\u6211\u4eec\u4e86\u89e3\u4eba\u7c7b\u5fae\u751f\u7269\u7ec4\u53ca\u5176\u5bf9\u6574\u4f53\u5065\u5eb7\u7684\u5f71\u54cd\u4ea7\u751f\u66f4\u5e7f\u6cdb\u7684\u5f71\u54cd\u3002\u5b83\u9f13\u52b1\u7814\u7a76\u4eba\u5458\u8003\u8651\u80a0\u9053\u6fc0\u7d20\u5982\u4f55\u4e0e\u4f53\u5185\u5176\u4ed6\u7cfb\u7edf\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u6709\u53ef\u80fd\u5728\u6cbb\u7597\u548c\u7ba1\u7406\u7cd6\u5c3f\u75c5\u3001\u5fc3\u8840\u7ba1\u95ee\u9898\u548c\u514d\u75ab\u529f\u80fd\u969c\u788d\u7b49\u6162\u6027\u75be\u75c5\u65b9\u9762\u627e\u5230\u521b\u65b0\u65b9\u6cd5\u3002\u76ee\u524d\u5bf9PYY\u548c\u7c7b\u4f3c\u5206\u5b50\u7684\u7814\u7a76\u4e5f\u53ef\u80fd\u6781\u5927\u5730\u4fc3\u8fdb\u4e2a\u6027\u5316\u533b\u7597\u7684\u53d1\u5c55\uff0c\u5373\u6839\u636e\u4e2a\u4eba\u7279\u5b9a\u7684\u8377\u5c14\u8499\u548c\u5fae\u751f\u7269\u7ec4\u7279\u5f81\u6765\u5b9a\u5236\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u7ed3\u8bba\uff1a\u80bd YY \u5728\u80a0\u9053\u5065\u5eb7\u4e2d\u7684\u65b0\u91cd\u8981\u6027<\/h2>\n<p>\u591a\u80bd YY \u5728\u98df\u6b32\u8c03\u8282\u548c\u514d\u75ab\u53cd\u5e94\u4e2d\u7684\u53cc\u91cd\u4f5c\u7528\u7684\u53d1\u73b0\uff0c\u51f8\u663e\u4e86\u4eba\u4f53\u5404\u79cd\u529f\u80fd\u4e4b\u95f4\u9519\u7efc\u590d\u6742\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u5b83\u4e0d\u4ec5\u52a0\u6df1\u4e86\u6211\u4eec\u5bf9\u80a0\u9053\u5065\u5eb7\u7684\u4e86\u89e3\uff0c\u8fd8\u4e3a\u672a\u6765\u6cbb\u7597\u6d88\u5316\u7cfb\u7edf\u75be\u75c5\u548c\u4fdd\u6301\u6574\u4f53\u5065\u5eb7\u63d0\u4f9b\u4e86\u6709\u524d\u666f\u7684\u89c1\u89e3\u3002<\/p>\n<p>\u6211\u4eec\u5c06\u7ee7\u7eed\u63a2\u7d22\u8ff7\u4eba\u7684\u751f\u7269\u79d1\u5b66\u4e16\u754c\uff0c\u7279\u522b\u662f\u80bd YY \u7b49\u5206\u5b50\u7684\u7a81\u7834\u6027\u4f5c\u7528\u3001 <a href=\"https:\/\/www.ahb-lab.com\/zh\/introductions\/\">AHB Lab<\/a> \u59cb\u7ec8\u7ad9\u5728\u8fd9\u4e9b\u521b\u65b0\u7684\u524d\u6cbf\u3002\u6211\u4eec\u62e5\u6709\u901a\u8fc7\u72ec\u7279\u7684\u5408\u6210\u751f\u7269\u5b66\u62df\u80bd\u5e73\u53f0\uff08SBPP\uff09\u5f00\u53d1\u5148\u8fdb\u751f\u7269\u5408\u6210\u80bd\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u8fd9\u4f7f\u6211\u4eec\u5904\u4e8e\u751f\u7269\u6280\u672f\u8fdb\u6b65\u7684\u6700\u524d\u6cbf\u3002\u5728 AHB \u5b9e\u9a8c\u5ba4\uff0c\u6211\u4eec\u4e0d\u4ec5\u8981\u5728\u751f\u7269\u6280\u672f\u9886\u57df\u5f00\u62d3\u8fdb\u53d6\uff0c\u8fd8\u8981\u4e3a\u73b0\u5b9e\u4e16\u754c\u4e2d\u7684\u5065\u5eb7\u6311\u6218\u5e26\u6765\u53d8\u9769\u6027\u7684\u89e3\u51b3\u65b9\u6848\u3002\u8bf7\u7ee7\u7eed\u5173\u6ce8\u6211\u4eec\u7684\u66f4\u591a\u89c1\u89e3\u548c\u66f4\u65b0\uff0c\u56e0\u4e3a\u6211\u4eec\u81f4\u529b\u4e8e\u8ba9\u60a8\u4e86\u89e3\u884c\u4e1a\u7684\u6700\u65b0\u53d1\u5c55\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>Peptide YY (PYY), a hormone traditionally known for its role in appetite regulation, has recently emerged as a key player in maintaining gut health and immunity. This new revelation, stemming from research at the University of Chicago, sheds light on the multifaceted functions of PYY, expanding our understanding of gut health and potential therapeutic approaches. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1733,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,12],"tags":[],"class_list":["post-1730","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-introduction","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Exploring Peptide YY: Balancing Hunger and Gut Immunity - AHB Lab<\/title>\n<meta name=\"description\" content=\"Explore AHB Lab&#039;s insights on the role of Peptide YY in appetite and immunity. 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