{"id":3347,"date":"2026-02-04T03:24:38","date_gmt":"2026-02-04T03:24:38","guid":{"rendered":"https:\/\/www.ahb-lab.com\/?p=3347"},"modified":"2026-03-18T04:17:31","modified_gmt":"2026-03-18T04:17:31","slug":"%e7%ac%ac%e4%b8%89%e4%bb%a3%e8%83%9c%e8%82%bd-%e5%be%9e%e7%85%89%e9%87%91%e8%a1%93%e5%88%b0%e7%94%9f%e7%89%a9%e7%b7%a8%e7%a8%8b%e5%be%9e%e7%85%89%e9%87%91%e8%a1%93%e5%88%b0%e7%94%9f%e7%89%a9%e7%b7%a8","status":"publish","type":"post","link":"https:\/\/www.ahb-lab.com\/zh\/company-news\/%e7%ac%ac%e4%b8%89%e4%bb%a3%e8%83%9c%e8%82%bd-%e5%be%9e%e7%85%89%e9%87%91%e8%a1%93%e5%88%b0%e7%94%9f%e7%89%a9%e7%b7%a8%e7%a8%8b%e5%be%9e%e7%85%89%e9%87%91%e8%a1%93%e5%88%b0%e7%94%9f%e7%89%a9%e7%b7%a8\/","title":{"rendered":"\u7b2c\u4e09\u4ee3\u80dc\u80bd-\u5f9e\u7149\u91d1\u8853\u5230\u751f\u7269\u7de8\u7a0b\u5f9e\u7149\u91d1\u8853\u5230\u751f\u7269\u7de8\u7a0b"},"content":{"rendered":"<h2><b>\u751f\u7269\u6d3b\u6027\u6750\u6599\u7684\u5178\u7bc4\u8f49\u79fb<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u5728\u7576\u524d\u7684\u751f\u7269\u6280\u8853\u8207\u88fd\u85e5\u7522\u696d\u4e2d\uff0c\u6211\u5011\u6b63\u8655\u65bc\u4e00\u500b\u95dc\u9375\u7684\u6b77\u53f2\u8f49\u6298\u9ede\u3002\u9577\u4e45\u4ee5\u4f86\uff0c\u80dc\u80bd\uff08Peptides\uff09- \u9019\u4e9b\u80fd\u5920\u7cbe\u6e96\u6307\u63ee\u7d30\u80de\u4fee\u5fa9\u3001\u518d\u751f\u8207\u4ee3\u8b1d\u7684\u6c28\u57fa\u9178\u93c8- \u88ab\u8996\u70ba\u91ab\u7642\u8207\u7f8e\u5bb9\u9818\u57df\u7684\u300c\u7687\u51a0\u4e0a\u7684\u5bf6\u77f3\u300d\u3002\u7136\u800c\uff0c\u53d7\u9650\u65bc\u50b3\u7d71\u5316\u5b78\u5408\u6210\u6280\u8853\u7684\u4f4e\u6548\u7387\u8207\u9ad8\u6c61\u67d3\uff0c\u80dc\u80bd\u7684\u61c9\u7528\u9577\u671f\u88ab\u300c\u9ec3\u91d1\u7d1a\u300d\u7684\u5b9a\u50f9\u6240\u675f\u7e1b\uff0c\u50c5\u80fd\u670d\u52d9\u65bc\u5c11\u6578\u7cbe\u82f1\u968e\u5c64\u6216\u7528\u65bc\u6cbb\u7642\u7f55\u898b\u75be\u75c5\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AHB Lab \u7368\u5bb6\u7684 <\/span><b>SBPP (Synthetic Biopeptide Production Platform) : \u5408\u6210\u751f\u7269\u80bd\u751f\u7522\u5e73\u53f0<\/b><span style=\"font-weight: 400;\">\u9019\u5834\u5f9e\u300c\u5316\u5b78\u66b4\u529b\u300d\u5230\u300c\u751f\u7269\u88fd\u9020\u300d\u7684\u6280\u8853\u9769\u547d\uff0c\u5982\u4f55\u5c07\u66fe\u7d93\u6bd4\u9ec3\u91d1\u6602\u8cb4\u5341\u500d\u7684\u300c\u6551\u547d\u9470\u5319\u300d\uff0c\u8f49\u5316\u70ba\u5927\u773e\u89f8\u624b\u53ef\u53ca\u7684\u300c\u767d\u83dc\u50f9\u300d\u9ed1\u79d1\u6280\u3002<\/span><\/p>\n<h2><b>\u9ec3\u91d1\u6a19\u6e96\u300d\u6642\u4ee3<\/b><\/h2>\n<h3><b>\u6b77\u53f2\u4f30\u503c\u8207\u793e\u6703\u5730\u4f4d<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u8981\u7406\u89e3\u7576\u524d\u6280\u8853\u9769\u547d\u7684\u9707\u61be\u6027\uff0c\u6211\u5011\u5fc5\u9808\u56de\u6eaf\u80dc\u80bd\u7d93\u6fdf\u7684\u6b77\u53f2\u8108\u7d61\u3002\u5728 20 \u4e16\u7d00\u672b\u81f3 21 \u4e16\u7d00\u521d\u7684\u5927\u90e8\u5206\u6642\u9593\u88e1\uff0c\u9ad8\u7d14\u5ea6\u3001\u91ab\u85e5\u7d1a\u7684\u751f\u7269\u6d3b\u6027\u80dc\u80bd\uff0c\u5176\u5e02\u5834\u4f30\u503c\u7d93\u5e38\u8207\u7a00\u571f\u91d1\u5c6c\u6216\u9802\u7d1a\u5bf6\u77f3\u76f8\u63d0\u4e26\u8ad6\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u6839\u64da\u6b77\u53f2\u5e02\u5834\u6578\u64da\u5206\u6790\uff0c\u7279\u5b9a\u5e8f\u5217\u7684\u9ad8\u7d14\u5ea6\u80dc\u80bd\uff08\u5c24\u5176\u662f\u9577\u93c8\u6216\u8907\u96dc\u7d50\u69cb\u80dc\u80bd\uff09\uff0c\u5176\u6bcf\u514b\u55ae\u50f9\u7d93\u5e38\u7a81\u7834 <\/span><b>500 \u81f3 1,000 \u7f8e\u5143<\/b><span style=\"font-weight: 400;\">\u5728\u67d0\u4e9b\u6975\u7aef\u60c5\u6cc1\u4e0b\uff0c\u9019\u4e00\u50f9\u683c\u751a\u81f3\u662f\u7576\u6642\u9ec3\u91d1\u50f9\u683c\u7684 10 \u5230 20 \u500d\u3002\u9019\u7a2e\u9a5a\u4eba\u7684\u50f9\u683c\u5dee\u7570\u69cb\u5efa\u4e86\u4e00\u9053\u5805\u56fa\u7684\u968e\u7d1a\u58c1\u58d8\uff1a<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u8cb4\u65cf\u91ab\u5b78\u7684\u8c61\u5fb5<\/b><span style=\"font-weight: 400;\">\u5b83\u4e0d\u50c5\u662f\u79d1\u5b78\u7684\u7d50\u6676\uff0c\u66f4\u662f\u8ca1\u5bcc\u8207\u5730\u4f4d\u7684\u8c61\u5fb5\u3002\u53ea\u6709\u90a3\u4e9b\u64c1\u6709\u7121\u9650\u8cc7\u6e90\u7684\u9802\u5c64\u5bcc\u8c6a\uff0c\u624d\u80fd\u8ca0\u64d4\u5f97\u8d77\u9019\u7a2e\u80fd\u5920\u300c\u9006\u8f49\u6642\u9593\u300d\u7684\u5fae\u89c0\u7269\u8cea\u3002<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u7814\u767c\u7684\u5922\u9b58<\/b><span style=\"font-weight: 400;\">\u5c0d\u65bc\u85e5\u7269\u7814\u767c\u8005\u800c\u8a00\uff0c\u9ad8\u6602\u7684\u539f\u6599\u6210\u672c\u610f\u5473\u8457\u6975\u9ad8\u7684\u8a66\u932f\u9580\u6abb\u3002\u8a31\u591a\u5177\u6709\u6f5b\u529b\u7684\u80dc\u80bd\u85e5\u7269\u5728\u81e8\u5e8a\u524d\u968e\u6bb5\u5c31\u88ab\u653e\u68c4\uff0c\u56e0\u70ba\u6295\u8cc7\u8005\u7121\u6cd5\u9810\u898b\u5176\u5546\u696d\u5316\u7684\u53ef\u80fd\u6027-\u300c\u5373\u4fbf\u85e5\u6709\u6548\uff0c\u8ab0\u8cb7\u5f97\u8d77\uff1f<\/span><\/li>\n<\/ul>\n<h3><b>\u5b9a\u50f9\u80cc\u5f8c\u7684\u771f\u76f8\uff1a\u4e26\u975e\u539f\u6599\u6602\u8cb4\uff0c\u800c\u662f\u6280\u8853\u843d\u5f8c<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u5927\u773e\u666e\u904d\u5b58\u5728\u4e00\u500b\u8aa4\u89e3\uff0c\u8a8d\u70ba\u80dc\u80bd\u4e4b\u6240\u4ee5\u6602\u8cb4\uff0c\u662f\u56e0\u70ba\u5176\u7d44\u6210\u539f\u6599\uff08\u6c28\u57fa\u9178\uff09\u7a00\u7f3a\u3002\u4e8b\u5be6\u4e0a\uff0c\u6c28\u57fa\u9178\u662f\u5730\u7403\u4e0a\u6700\u8c50\u5bcc\u7684\u6709\u6a5f\u7269\u8cea\u4e4b\u4e00\u3002<\/span><\/p>\n<h4><b>\u56fa\u76f8\u5408\u6210\uff08SPPS\uff09\u7684\u6280\u8853\u74f6\u9838<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">\u50b3\u7d71\u7684\u80dc\u80bd\u88fd\u9020\u4e3b\u8981\u4f9d\u8cf4\u65bc 1963 \u5e74\u7531 Bruce Merrifield \u767c\u660e\u7684 <\/span><b>\u56fa\u76f8\u80dc\u80bd\u5408\u6210\u6cd5\uff08Solid-Phase Peptide Synthesis, SPPS\uff09<\/b><span style=\"font-weight: 400;\">\u96d6\u7136\u9019\u9805\u6280\u8853\u7372\u5f97\u4e86\u8afe\u8c9d\u723e\u734e\u4e26\u958b\u555f\u4e86\u80dc\u80bd\u5316\u5b78\u7684\u5927\u9580\uff0c\u4f46\u5f9e\u5de5\u696d\u751f\u7522\u7684\u89d2\u5ea6\u4f86\u770b\uff0c\u5b83\u672c\u8cea\u4e0a\u662f\u4e00\u7a2e\u300c\u5f37\u884c\u7d44\u88dd\u300d\u7684\u904e\u7a0b\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u6211\u5011\u53ef\u4ee5\u5c07 spps \u5f62\u8c61\u5730\u6bd4\u55bb\u70ba\u300c\u5728\u6c34\u6ce5\u652a\u62cc\u6a5f\u88e1\u7d44\u88dd\u6a02\u9ad8\u300d\uff1a<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u96a8\u6a5f\u78b0\u649e\u8207\u5f37\u8feb\u9375\u7d50<\/b><span style=\"font-weight: 400;\">\u5728\u5316\u5b78\u5408\u6210\u4e2d\uff0c\u79d1\u5b78\u5bb6\u5c07\u5927\u91cf\u7684\u6c28\u57fa\u9178\uff08\u6a02\u9ad8\u7a4d\u6728\uff09\u6295\u5165\u53cd\u61c9\u5668\uff0c\u4e26\u52a0\u5165\u9ad8\u6d3b\u6027\u7684<\/span><span style=\"font-weight: 400;\">\u5076<\/span><span style=\"font-weight: 400;\">\u5408\u5291\uff08\u81a0\u6c34\uff09\u8207\u6709\u6bd2\u6eb6\u5291\u3002\u70ba\u4e86\u8b93\u5169\u500b\u6c28\u57fa\u9178\u5206\u5b50\u5728\u6b63\u78ba\u7684\u4f4d\u7f6e\u9023\u63a5\uff0c\u5fc5\u9808\u65bd\u52a0\u9ad8\u6eab\u3001\u9ad8\u58d3\uff0c\u4e26\u4f7f\u7528\u904e\u91cf\u7684\u53cd\u61c9\u7269\u4f86\u63a8\u52d5\u5316\u5b78\u5e73\u8861\u3002<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u7acb\u9ad4\u5316\u5b78\u7684\u6df7\u4e82\uff08Racemization\uff09<\/b><span style=\"font-weight: 400;\">\uff1a\u6c28\u57fa\u9178\u5177\u6709<\/span><span style=\"font-weight: 400;\">\u638c<\/span><span style=\"font-weight: 400;\">\u6027\uff08\u5de6\u65cb L-form \u8207 \u53f3\u65cb D-form\uff09\u3002\u5728\u751f\u7269\u9ad4\u5167\uff0c\u9176\u80fd\u7cbe\u78ba\u8b58\u5225\u4e26\u53ea\u4f7f\u7528 L-\u578b\u6c28\u57fa\u9178\u3002\u7136\u800c\uff0c\u5316\u5b78\u5408\u6210\u7684\u5287\u70c8\u53cd\u61c9\u74b0\u5883\u5f80\u5f80\u5c0e\u81f4\u300c\u6d88\u65cb\u5316\u300d\uff0c\u5373\u539f\u672c\u61c9\u8a72\u662f L-\u578b\u7684\u6c28\u57fa\u9178\u8b8a\u6210\u4e86 D-\u578b\u3002\u9019\u5c31\u50cf\u662f\u628a\u4e00\u584a\u5713\u5f62\u7684\u7a4d\u6728\u5f37\u884c\u585e\u9032\u65b9\u5f62\u7684\u5b54\u6d1e\u88e1\u3002\u7d50\u679c\u7522\u751f\u4e86\u5927\u91cf\u7684\u300c\u7570\u69cb\u9ad4\u300d-\u5316\u5b78\u5f0f\u6b63\u78ba\uff0c\u4f46\u4e09\u7dad\u7d50\u69cb\u626d\u66f2\u7684\u5206\u5b50\u3002\u9019\u4e9b\u300c\u7578\u5f62\u300d\u5206\u5b50\u4e0d\u50c5\u7121\u6548\uff0c\u9084\u53ef\u80fd\u88ab\u514d\u75ab\u7cfb\u7d71\u8996\u70ba\u7570\u7269\uff0c\u5f15\u767c\u56b4\u91cd\u7684\u904e\u654f\u53cd\u61c9\u3002<\/span><\/li>\n<\/ul>\n<h4><b>\u7d14\u5316\u7684\u4ee3\u50f9\uff1a\u6307\u6578\u7d1a\u7684\u7522\u7387\u8870\u6e1b<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">\u5316\u5b78\u5408\u6210\u7684\u53e6\u4e00\u500b\u81f4\u547d\u50b7\u662f\u7522\u7387\u7684\u6307\u6578\u7d1a\u8870\u6e1b\u3002\u5047\u8a2d\u5408\u6210\u4e00\u500b 30 \u6c28\u57fa\u9178\u9577\u7684\u80dc\u80bd\uff0c\u6bcf\u4e00\u6b65\u53cd\u61c9\u7684\u7522\u7387\u5373\u4f7f\u9ad8\u9054 99%\uff08\u9019\u5728\u5316\u5b78\u4e0a\u5df2\u7d93\u662f\u975e\u5e38\u7406\u60f3\u7684\u72c0\u6cc1\uff09\uff0c\u7d93\u904e 29 \u6b65\u53cd\u61c9\u5f8c\uff0c\u6700\u7d42\u7684\u7406\u8ad6\u7522\u7387\u50c5\u5269\u4e0b\u7d04 74%\u300274%\u3002\u800c\u5728\u73fe\u5be6\u4e2d\uff0c\u8a31\u591a\u6b65\u9a5f\u7684\u7522\u7387\u53ef\u80fd\u53ea\u6709 90% \u6216\u66f4\u4f4e\uff0c\u9019\u5c0e\u81f4\u6700\u7d42\u7522\u7269\u4e2d\uff0c\u76ee\u6a19\u80dc\u80bd\u53ef\u80fd\u53ea\u4f54\u4e0d\u5230 10%\uff0c\u5176\u9918 90% \u90fd\u662f\u7d50\u69cb\u932f\u8aa4\u7684\u526f\u7522\u7269\uff08Truncated sequences\u3001\u522a\u9664\u5e8f\u5217\uff09\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u70ba\u4e86\u5f9e\u9019 90% \u7684\u300c\u5783\u573e\u300d\u4e2d\u63d0\u7149\u51fa\u90a3 10% \u7684\u300c\u9ec3\u91d1\u300d\uff0c\u85e5\u5ee0\u5fc5\u9808\u4f7f\u7528\u6602\u8cb4\u7684\u9ad8\u6548\u6db2\u76f8\u5c64\u6790\uff08hplc\uff09\u9032\u884c\u53cd\u8986\u7d14\u5316\u3002 \u9019\u5c31\u662f\u70ba\u4ec0\u9ebc\u5e02\u9762\u4e0a\u7684\u80dc\u80bd\u5206\u70ba\u300c\u79d1\u7814\u7d1a\uff08\u7c97\u54c1\uff09\u300d\u548c\u300c\u91ab\u85e5\u7d1a\uff0899%\u7d14\u5ea6\uff09\u300d\uff0c\u5169\u8005\u50f9\u683c\u76f8\u5dee\u767e\u500d\u7684\u539f\u56e0-\u4f60\u652f\u4ed8\u7684\u4e0d\u662f\u539f\u6599\u8cbb\uff0c\u800c\u662f\u5c07\u5783\u573e\u5206\u96e2\u51fa\u53bb\u7684\u300c\u6e05\u6f54\u8cbb\u300d\u3002<\/span><\/p>\n<h2><b>\u6280\u8853\u5f9e\u300c\u5316\u5b78\u66b4\u529b\u300d\u5230\u300c\u751f\u7269\u7de8\u7a0b<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u7576\u4e00\u500b\u884c\u696d\u53d7\u56f0\u65bc\u6210\u672c\u7d50\u69cb\u7121\u6cd5\u81ea\u62d4\u6642\uff0c\u5f80\u5f80\u9700\u8981\u4e00\u7a2e\u4f86\u81ea\u66f4\u9ad8\u7dad\u5ea6\u7684\u6280\u8853\u4f86\u9032\u884c\u300c\u964d\u7dad\u6253\u64ca\u300d\u3002\u5728\u80dc\u80bd\u9818\u57df\uff0c\u9019\u5834\u9769\u547d\u5c31\u662f\u5f9e <\/span><b>\u5316\u5b78\u5408\u6210<\/b><span style=\"font-weight: 400;\"> \u8f49\u5411 <\/span><b>\u751f\u7269\u5408\u6210\uff08Biosynthesis\uff09<\/b><span style=\"font-weight: 400;\">\uff0c\u5177\u9ad4\u9ad4\u73fe\u70ba AHB Lab \u7684 <\/span><b>SBPP \u5e73\u53f0<\/b><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<h3><b>sbpp \u5e73\u53f0\u7684\u6838\u5fc3\u908f\u8f2f\uff1a\u7de8\u7a0b\u751f\u547d<\/b><\/h3>\n<p><b>SBPP<\/b><span style=\"font-weight: 400;\">\u4ee3\u8868\u4e86\u4e00\u7a2e\u88fd\u9020\u54f2\u5b78\u7684\u6839\u672c\u8f49\u8b8a\u3002\u5b83\u4e0d\u518d\u8a66\u5716\u7528\u5916\u529b\u53bb\u300c\u6a21\u4eff\u300d\u81ea\u7136\u7684\u5316\u5b78\u9375\u7d50\uff0c\u800c\u662f\u76f4\u63a5\u300c\u5fb5\u7528\u300d\u5927\u81ea\u7136\u5df2\u7d93\u6f14\u5316\u4e86\u6578\u5341\u5104\u5e74\u7684\u86cb\u767d\u8cea\u88fd\u9020\u5de5\u5ee0-\u3002<\/span><span style=\"font-weight: 400;\">\u5fae\u751f\u7269<\/span><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<h4><b>\u9175\u6bcd\u83cc\u4f5c\u70ba\u5948\u7c73\u7d1a 3D \u5370\u8868\u6a5f<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">sb inpp \u6280\u8853\u4e2d\uff0c\u5fae\u751f\u7269\uff08\u7279\u5225\u662f\u7d93\u904e\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u7684\u9175\u6bcd\u83cc <\/span><i><span style=\"font-weight: 400;\">\u9175\u6bcd\u83cc<\/span><\/i><span style=\"font-weight: 400;\"> \u6216 <\/span><i><span style=\"font-weight: 400;\">Pichia pastoris<\/span><\/i><span style=\"font-weight: 400;\">\u88ab\u8f49\u5316\u70ba\u5fae\u578b\u7684\u3001\u53ef\u7de8\u7a0b\u7684\u751f\u7522\u55ae\u5143\u3002<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u57fa\u56e0\u6307\u4ee4\u7684\u8f38\u5165<\/b><span style=\"font-weight: 400;\">\u9019\u76f8\u7576\u65bc\u5c07 cad \u8a2d\u8a08\u5716\u4e0a\u50b3\u5230 3d \u5370\u8868\u6a5f\u3002<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u4ee3\u8b1d\u5de5\u7a0b\u7684\u512a\u5316<\/b><span style=\"font-weight: 400;\">\u9019\u5c31\u50cf\u662f\u8abf\u6574\u4e86\u4e00\u689d\u751f\u7522\u7dda\u7684\u53c3\u6578\uff0c\u4f7f\u5176\u5168\u901f\u904b\u8f49\u751f\u7522\u55ae\u4e00\u7522\u54c1\u3002<\/span><\/li>\n<\/ul>\n<h4><b>\u8cbb\u7c73\u7d1a\u7684\u7cbe\u6e96\u5ea6<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">\u8207\u5316\u5b78\u5408\u6210\u7684\u300c\u66b4\u529b\u652a\u62cc\u300d\u4e0d\u540c\uff0c\u751f\u7269\u5408\u6210\u662f\u5728\u6838\u7cd6\u9ad4\uff08Ribosome\uff09\u4e0a\u9032\u884c\u7684\u3002\u6838\u7cd6\u9ad4\u662f\u81ea\u7136\u754c\u6700\u7cbe\u5bc6\u7684\u5948\u7c73\u6a5f\u5668\uff0c\u5b83\u56b4\u683c\u6309\u7167 mRNA \u7684\u6307\u4ee4\uff0c\u4e00\u6b21\u4e00\u500b\u6c28\u57fa\u9178\u5730\u7d44\u88dd\u80dc\u80bd\u93c8\u3002<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u96f6\u6d88\u65cb\u5316<\/b><span style=\"font-weight: 400;\">\uff1a\u751f\u7269\u9176\u5177\u6709\u7d55\u5c0d\u7684\u7acb\u9ad4\u9078\u64c7\u6027\uff0c\u53ea\u6703\u4f7f\u7528 L-\u578b\u6c28\u57fa\u9178\u3002\u9019\u610f\u5473\u8457 SBPP \u751f\u7522\u51fa\u7684\u80dc\u80bd\uff0c\u5176\u5149\u5b78\u7d14\u5ea6\uff08Optical Purity\uff09\u5e7e\u4e4e\u662f 100%\uff0c\u5b8c\u5168\u907f\u514d\u4e86\u300c\u7578\u5f62\u300d\u5206\u5b50\u7684\u7522\u751f\u3002<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>100% \u4eba\u9ad4\u540c\u6e90\uff08Human-Identical\uff09<\/b><span style=\"font-weight: 400;\">\u9019\u78ba\u4fdd\u4e86\u5b8c\u7f8e\u7684\u53d7\u9ad4\u7d50\u5408\u89aa\u548c\u529b\uff08Receptor Affinity\uff09\u548c\u6975\u4f4e\u7684\u514d\u75ab\u539f\u6027\uff08Immunogenicity\uff09\u3002<\/span><\/li>\n<\/ul>\n<h3><b>\u6210\u672c\u7d50\u69cb\u7684\u5fb9\u5e95\u985b\u8986\uff1a\u767d\u83dc\u50f9\u7d93\u6fdf\u5b78<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\"\u767d\u83dc\u50f9\u300d\u9019\u500b\u8a5e\u807d\u8d77\u4f86\u8a87\u5f35\uff0c\u4f46\u5728\u751f\u7269\u767c\u9175\u7684\u7d93\u6fdf\u6a21\u578b\u4e0b\uff0c\u5b83\u662f\u771f\u5be6\u5b58\u5728\u7684\u7269\u7406\u898f\u5f8b\u3002<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u539f\u6599\u6210\u672c\u7684\u53bb\u5546\u54c1\u5316<\/b><span style=\"font-weight: 400;\">\uff1a\u5316\u5b78\u5408\u6210\u4f9d\u8cf4\u65bc\u6602\u8cb4\u7684\u53d7\u4fdd\u8b77\u6c28\u57fa\u9178\uff08Fmoc-amino acids\uff09\u548c\u7279\u6b8a\u7684<\/span><span style=\"font-weight: 400;\">\u5076<\/span><span style=\"font-weight: 400;\">\u5408\u8a66\u5291\u3002\u800c\u751f\u7269\u5408\u6210\u7684\u539f\u6599\u662f <\/span><b>\u7cd6\uff08\u8461\u8404\u7cd6\/\u8517\u7cd6\uff09\u3001\u6c34\u548c\u5fae\u91cf\u7926\u7269\u8cea<\/b><span style=\"font-weight: 400;\">\u9019\u4e9b\u90fd\u662f\u5927\u5b97\u8fb2\u696d\u5546\u54c1\uff0c\u50f9\u683c\u6975\u5176\u4f4e\u5ec9\u4e14\u7a69\u5b9a\u3002<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u898f\u6a21\u6548\u61c9\u7684\u5dee\u7570<\/b><span style=\"font-weight: 400;\">\uff1a\u5316\u5b78\u5408\u6210\u7684\u653e\u5927\uff08Scale-up\uff09\u975e\u5e38\u56f0\u96e3\uff0c\u901a\u5e38\u9700\u8981\u4e26\u806f\u66f4\u591a\u7684\u53cd\u61c9\u5668\uff0c\u6210\u672c\u5448\u7dda\u6027\u589e\u9577\u3002\u800c\u751f\u7269\u767c\u9175\u5177\u6709\u6307\u6578\u7d1a\u7684\u64f4\u589e\u80fd\u529b\u3002<\/span><span style=\"font-weight: 400;\">\u69fd<\/span><span style=\"font-weight: 400;\">\u8207\u4e00\u500b 50,000 \u516c\u5347\u7684\u767c\u9175<\/span><span style=\"font-weight: 400;\">\u69fd<\/span><span style=\"font-weight: 400;\">\u9019\u5c31\u662f\u70ba\u4ec0\u9ebc\u5564\u9152\uff08\u767c\u9175\u7522\u54c1\uff09\u53ef\u4ee5\u6bd4\u6c34\u8cb4\u4e0d\u4e86\u591a\u5c11\uff0c\u800c\u5316\u5b78\u85e5\u54c1\u537b\u50f9\u683c\u9ad8\u6602\u7684\u539f\u56e0\u3002<\/span><\/li>\n<\/ul>\n<table>\n<tbody>\n<tr>\n<td><b>\u6bd4\u8f03\u7dad\u5ea6<\/b><\/td>\n<td><b>\u5316\u5b78\u5408\u6210 (Solid-Phase Synthesis)<\/b><\/td>\n<td><b>\u751f\u7269\u7de8\u7a0b (AHB Lab sbpp)<\/b><\/td>\n<td><b>\u5546\u696d\u5f71\u97ff (B2B\/B2C)<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>\u6838\u5fc3\u6a5f\u5236<\/b><\/td>\n<td><span style=\"font-weight: 400;\">\u5916\u90e8\u80fd\u91cf\u9a45\u52d5\u7684\u5f37\u5236\u5316\u5b78\u9375\u7d50<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u7d30\u80de\u5167\u90e8\u57fa\u56e0\u6307\u4ee4\u9a45\u52d5\u7684\u9176\u4fc3\u5408\u6210<\/span><\/td>\n<td><b>\u88fd\u7a0b \uff1a <\/b><span style=\"font-weight: 400;\">\u5f9e\u300c\u4eba\u5de5\u5408\u6210\u300d\u8f49\u5411\u300c\u751f\u7269\u81ea\u7136\u751f\u9577\u300d\u3002<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>\u7acb\u9ad4\u7d50\u69cb<\/b><\/td>\n<td><span style=\"font-weight: 400;\">\u6613\u767c\u751f\u6d88\u65cb\u5316\uff0c\u5b58\u5728\u7570\u69cb\u9ad4\u96dc\u8cea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">100% l-\u578b\u7d50\u69cb\uff0c\u5b8c\u7f8e\u4e09\u7dad\u647a\u758a<\/span><\/td>\n<td><b>\u5b89\u5168\u6027<\/b><span style=\"font-weight: 400;\">\u751f\u7269\u5408\u6210\u7522\u54c1\u66f4\u9069\u5408\u654f\u611f\u808c\u8207\u91ab\u7642\u7528\u9014\u3002<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>\u74b0\u5883\u8db3\u8de1<\/b><\/td>\n<td><span style=\"font-weight: 400;\">\u6975\u9ad8 (pmi &gt; 10,000) \uff0c\u5927\u91cf\u6709\u6a5f\u6eb6\u5291\u5ee2\u68c4\u7269<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u4f4e\uff0c\u4e3b\u8981\u5ee2\u68c4\u7269\u70ba\u6c34\u548c\u751f\u7269\u8cea (\u53ef\u964d\u89e3)<\/span><\/td>\n<td><b>ESG \u884c\u92b7<\/b><span style=\"font-weight: 400;\">\u7b26\u5408\u300c\u7da0\u8272\u5316\u5b78\u300d\u8207\u300c\u6c38\u7e8c\u767c\u5c55\u300d\u8da8\u52e2\u3002<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>\u64f4\u5c55\u6027<\/b><\/td>\n<td><span style=\"font-weight: 400;\">\u7dda\u6027\u64f4\u5c55\uff0c\u6210\u672c\u96a8\u7522\u91cf\u4e0b\u964d\u7de9\u6162<\/span><\/td>\n<td><span style=\"font-weight: 400;\">\u6307\u6578\u64f4\u5c55\uff0c\u898f\u6a21\u8d8a\u5927\u6210\u672c\u8d8a\u4f4e<\/span><\/td>\n<td><b>\u5b9a\u50f9\u7b56\u7565<\/b><span style=\"font-weight: 400;\">\u4f7f\u5f97\u9ad8\u6fc3\u5ea6\u80dc\u80bd\u7522\u54c1\u6210\u70ba\u5927\u773e\u6d88\u8cbb\u54c1\u6210\u70ba\u53ef\u80fd\u3002<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><b>\u7da0\u8272\u5316\u5b78\u8207\u4f9b\u61c9\u93c8\u97cc\u6027<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">AHB Lab \u7684 sbpp \u6280\u8853\u6b63\u597d\u5207\u4e2d\u4e86\u7576\u524d\u5168\u7403\u4f9b\u61c9\u93c8\u7684\u4e09\u5927\u7126\u616e\uff1a<\/span><b>\u6c38\u7e8c\u6027\uff08Sustainability\uff09\u3001\u7a69\u5b9a\u6027\uff08Stability\uff09\u8207\u5b89\u5168\u6027\uff08Safety\uff09<\/b><span style=\"font-weight: 400;\">\u3002<\/span><\/p>\n<h3><b>\u64fa\u812b\u77f3\u6cb9\u4f9d\u8cf4\u7684\u7da0\u8272\u4f9b\u61c9\u93c8<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u5316\u5b78\u5408\u6210\u80dc\u80bd\u9ad8\u5ea6\u4f9d\u8cf4\u77f3\u5316\u5de5\u696d\u3002\u5176\u95dc\u9375\u6eb6\u5291\u5982 dmf\uff08\u4e8c\u7532\u57fa\u7532\u91af\u80fa\uff09\u548c nmp\uff08n-\u7532\u57fa\u5421\u54af\u70f7\u916e\uff09\u90fd\u88ab\u6b50\u76df\u9054\u5230 \u6cd5\u898f\u5217\u70ba\u300c\u9ad8\u5ea6\u95dc\u6ce8\u7269\u8cea\uff08svhc\uff09\u300d\uff0c\u9762\u81e8\u56b4\u683c\u7684\u76e3\u7ba1\u751a\u81f3\u7981\u7528\u98a8\u96aa\u3002<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>PMI \u6307\u6a19\u7684\u52dd\u5229<\/b><span style=\"font-weight: 400;\">\u5316\u5b78\u5408\u6210\u80dc\u80bd\u7684 PMI \u901a\u5e38\u9ad8\u9054 3,000 \u81f3 15,000\uff08\u5373\u751f\u7522 1kg \u80dc\u80bd\u9700\u8981 3-15 \u5678\u7684\u7269\u6599\uff09\uff0c\u800c\u751f\u7269\u5408\u6210\u7684 PMI \u901a\u5e38\u4f4e\u65bc 1,000\uff0c\u4e14\u5927\u90e8\u5206\u5ee2\u68c4\u7269\u662f\u6c34\u548c\u751f\u7269\u8cea\u3002<\/span><\/li>\n<\/ul>\n<h3><b>\u6279\u6b21\u4e00\u81f4\u6027\uff08Batch-to-Batch Consistency\uff09\u7684\u54c1\u8cea\u4fdd\u8b49<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u5316\u5b78\u5408\u6210\u53d7\u9650\u65bc\u64cd\u4f5c\u74b0\u5883\u7684\u5fae\u5c0f\u8b8a\u5316\uff08\u6eab\u5ea6\u3001\u6fd5\u5ea6\u3001\u652a\u62cc\u901f\u5ea6\uff09\uff0c\u4e0d\u540c\u6279\u6b21\u4e4b\u9593\u7684\u54c1\u8cea\u6ce2\u52d5\u8f03\u5927\u3002 \u9019\u5c0d\u65bc\u9700\u8981\u9577\u671f\u7a69\u5b9a\u4f9b\u8ca8\u7684\u5316\u599d\u54c1\u54c1\u724c\u662f\u500b\u707d\u96e3\u3002<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u751f\u7269<\/b><b>\u5408<\/b><b>\u6210<\/b><b>\u7684\u7cbe\u78ba\u6027<\/b><span style=\"font-weight: 400;\">\uff1aSBPP \u5229\u7528\u7684\u662f<\/span><span style=\"font-weight: 400;\">\u70ba\u5fae\u751f\u7269<\/span><span style=\"font-weight: 400;\">\u4e00\u65e6\u83cc\u7a2e\u5eab\u5efa\u7acb\uff0c\u6bcf\u4e00\u6b21\u767c\u9175\u90fd\u662f\u5c0d\u4e0a\u4e00\u6b21\u7684\u5b8c\u7f8e\u8907\u88fd\u3002<\/span><b>\u6279\u6b21\u4e00\u81f4\u6027<\/b><span style=\"font-weight: 400;\">\u8b93\u914d\u65b9\u5e2b\u5728\u8a2d\u8a08\u7522\u54c1\u6642\uff0c\u7121\u9700\u64d4\u5fc3\u539f\u6599\u54c1\u8cea\u6ce2\u52d5\u5c0e\u81f4\u7684\u7522\u54c1\u6027\u72c0\u6539\u8b8a\uff08\u5982\u984f\u8272\u3001\u6c23\u5473\u3001\u9ecf\u5ea6\u7684\u8b8a\u5316\uff09\u3002<\/span><\/li>\n<\/ul>\n<h2><b>\u5065\u5eb7\u81ea\u7531\u7684\u6642\u4ee3\u5df2\u4f86\u81e8<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u5f9e\u5316\u5b78\u5408\u6210\u7684\u300c\u8cb4\u65cf\u85e5\u300d\u5230\u751f\u7269\u7de8\u7a0b\u7684\u300c\u65e5\u7528\u54c1\u300d\uff0c\u6211\u5011\u6b63\u5728\u898b\u8b49\u4e00\u5834\u91ab\u7642\u8207\u7f8e\u5bb9\u7684\u6c11\u4e3b\u5316\u9769\u547d\u3002 \u597d\u6771\u897f\u4e4b\u6240\u4ee5\u8cb4\uff0c\u662f\u56e0\u70ba\u6280\u8853\u7684\u5c40\u9650\uff1b\u800c\u79d1\u6280\u7684\u7d42\u6975\u610f\u7fa9\uff0c\u5c31\u662f\u628a\u300c\u5929\u50f9\u300d\u8b8a\u6210\u300c\u767d\u83dc\u50f9\u300d\uff0c\u8b93\u6bcf\u500b\u4eba\u90fd\u80fd\u4eab\u6709\u5065\u5eb7\u7684\u6b0a\u5229\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5c0d\u65bc\u54c1\u724c\u5546\uff08b2b\uff09\u800c\u8a00\uff0c\u73fe\u5728\u662f\u64c1\u62b1 <\/span><b>SBPP \u6280\u8853<\/b><span style=\"font-weight: 400;\"> \u9019\u4e0d\u50c5\u662f\u6210\u672c\u7684\u512a\u52e2\uff0c\u66f4\u662f <\/span><b>ESG \u6c38\u7e8c\u767c\u5c55<\/b><span style=\"font-weight: 400;\"> \u8207 <\/span><b>\u7522\u54c1\u6548\u80fd<\/b><span style=\"font-weight: 400;\"> \u5225\u8b93\u60a8\u7684\u54c1\u724c\u505c\u7559\u5728\u300c\u5316\u5b78\u66b4\u529b\u300d\u7684\u820a\u6642\u4ee3\uff0c\u52a0\u5165\u9019\u5834\u751f\u7269\u7de8\u7a0b\u7684\u9769\u547d\u5427\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u60f3\u4e86\u89e3\u5982\u4f55\u5c07 AHB Lab \u6280\u8853\u61c9\u7528\u65bc\u60a8\u7684\u7522\u54c1\u7dda\u55ce\uff1f<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>\u751f\u7269\u6d3b\u6027\u6750\u6599\u7684\u5178\u7bc4\u8f49\u79fb \u5728\u7576\u524d\u7684\u751f\u7269\u6280\u8853\u8207\u88fd\u85e5\u7522\u696d\u4e2d\uff0c\u6211\u5011\u6b63\u8655\u65bc\u4e00\u500b\u95dc\u9375\u7684\u6b77\u53f2\u8f49\u6298\u9ede\u3002\u9577\u4e45\u4ee5\u4f86\uff0c\u80dc\u80bd\uff08Peptides\uff09\u2014 \u9019\u4e9b\u80fd\u5920\u7cbe\u6e96\u6307\u63ee\u7d30\u80de\u4fee\u5fa9\u3001\u518d\u751f\u8207\u4ee3\u8b1d\u7684\u6c28\u57fa\u9178\u93c8\u2014\u2014\u88ab\u8996\u70ba\u91ab\u7642\u8207\u7f8e\u5bb9\u9818\u57df\u7684\u300c\u7687\u51a0\u4e0a\u7684\u5bf6\u77f3\u300d\u3002\u7136\u800c\uff0c\u53d7\u9650\u65bc\u50b3\u7d71\u5316\u5b78\u5408\u6210\u6280\u8853\u7684\u4f4e\u6548\u7387\u8207\u9ad8\u6c61\u67d3\uff0c\u80dc\u80bd\u7684\u61c9\u7528\u9577\u671f\u88ab\u300c\u9ec3\u91d1\u7d1a\u300d\u7684\u5b9a\u50f9\u6240\u675f\u7e1b\uff0c\u50c5\u80fd\u670d\u52d9\u65bc\u5c11\u6578\u7cbe\u82f1\u968e\u5c64\u6216\u7528\u65bc\u6cbb\u7642\u7f55\u898b\u75be\u75c5\u3002 AHB Lab \u7368\u5bb6\u7684 SBPP (Synthetic Biopeptide Production Platform) : \u5408\u6210\u751f\u7269\u80bd\u751f\u7522\u5e73\u53f0\uff0c \u900f\u904e\u751f\u7269\u7de8\u7a0b\u6280\u8853\uff0c\u6253\u7834\u50b3\u7d71\u300c\u56fa\u76f8\u5408\u6210\uff08SPPS\uff09\u300d\u7684\u6210\u672c\u8207\u6280\u8853\u58c1\u58d8\u3002\u9019\u5834\u5f9e\u300c\u5316\u5b78\u66b4\u529b\u300d\u5230\u300c\u751f\u7269\u88fd\u9020\u300d\u7684\u6280\u8853\u9769\u547d\uff0c\u5982\u4f55\u5c07\u66fe\u7d93\u6bd4\u9ec3\u91d1\u6602\u8cb4\u5341\u500d\u7684\u300c\u6551\u547d\u9470\u5319\u300d\uff0c\u8f49\u5316\u70ba\u5927\u773e\u89f8\u624b\u53ef\u53ca\u7684\u300c\u767d\u83dc\u50f9\u300d\u9ed1\u79d1\u6280\u3002 \u80dc\u80bd\u7684\u300c\u9ec3\u91d1\u6a19\u6e96\u300d\u6642\u4ee3 \u6b77\u53f2\u4f30\u503c\u8207\u793e\u6703\u5730\u4f4d \u8981\u7406\u89e3\u7576\u524d\u6280\u8853\u9769\u547d\u7684\u9707\u61be\u6027\uff0c\u6211\u5011\u5fc5\u9808\u56de\u6eaf\u80dc\u80bd\u7d93\u6fdf\u7684\u6b77\u53f2\u8108\u7d61\u3002\u5728 20 \u4e16\u7d00\u672b\u81f3 21 \u4e16\u7d00\u521d\u7684\u5927\u90e8\u5206\u6642\u9593\u88e1\uff0c\u9ad8\u7d14\u5ea6\u3001\u91ab\u85e5\u7d1a\u7684\u751f\u7269\u6d3b\u6027\u80dc\u80bd\uff0c\u5176\u5e02\u5834\u4f30\u503c\u7d93\u5e38\u8207\u7a00\u571f\u91d1\u5c6c\u6216\u9802\u7d1a\u5bf6\u77f3\u76f8\u63d0\u4e26\u8ad6\u3002 \u6839\u64da\u6b77\u53f2\u5e02\u5834\u6578\u64da\u5206\u6790\uff0c\u7279\u5b9a\u5e8f\u5217\u7684\u9ad8\u7d14\u5ea6\u80dc\u80bd\uff08\u5c24\u5176\u662f\u9577\u93c8\u6216\u8907\u96dc\u7d50\u69cb\u80dc\u80bd\uff09\uff0c\u5176\u6bcf\u514b\u55ae\u50f9\u7d93\u5e38\u7a81\u7834 500 \u81f3 1,000 \u7f8e\u5143\uff0c\u5728\u67d0\u4e9b\u6975\u7aef\u60c5\u6cc1\u4e0b\uff0c\u9019\u4e00\u50f9\u683c\u751a\u81f3\u662f\u7576\u6642\u9ec3\u91d1\u50f9\u683c\u7684 10 \u5230 20 \u500d\u3002\u9019\u7a2e\u9a5a\u4eba\u7684\u50f9\u683c\u5dee\u7570\u69cb\u5efa\u4e86\u4e00\u9053\u5805\u56fa\u7684\u968e\u7d1a\u58c1\u58d8\uff1a \u8cb4\u65cf\u91ab\u5b78\u7684\u8c61\u5fb5\uff1a\u5728\u6297\u8870\u8001\u91ab\u5b78\u9818\u57df\uff0c\u80dc\u80bd\u7642\u6cd5\u88ab\u7a31\u70ba\u300c\u4e0a\u5e1d\u4e4b\u624b\u300d\u3002\u5b83\u4e0d\u50c5\u662f\u79d1\u5b78\u7684\u7d50\u6676\uff0c\u66f4\u662f\u8ca1\u5bcc\u8207\u5730\u4f4d\u7684\u8c61\u5fb5\u3002\u53ea\u6709\u90a3\u4e9b\u64c1\u6709\u7121\u9650\u8cc7\u6e90\u7684\u9802\u5c64\u5bcc\u8c6a\uff0c\u624d\u80fd\u8ca0\u64d4\u5f97\u8d77\u9019\u7a2e\u80fd\u5920\u300c\u9006\u8f49\u6642\u9593\u300d\u7684\u5fae\u89c0\u7269\u8cea\u3002 \u7814\u767c\u7684\u5922\u9b58\uff1a\u5c0d\u65bc\u85e5\u7269\u7814\u767c\u8005\u800c\u8a00\uff0c\u9ad8\u6602\u7684\u539f\u6599\u6210\u672c\u610f\u5473\u8457\u6975\u9ad8\u7684\u8a66\u932f\u9580\u6abb\u3002\u8a31\u591a\u5177\u6709\u6f5b\u529b\u7684\u80dc\u80bd\u85e5\u7269\u5728\u81e8\u5e8a\u524d\u968e\u6bb5\u5c31\u88ab\u653e\u68c4\uff0c\u56e0\u70ba\u6295\u8cc7\u8005\u7121\u6cd5\u9810\u898b\u5176\u5546\u696d\u5316\u7684\u53ef\u80fd\u6027\u2014\u300c\u5373\u4fbf\u85e5\u6709\u6548\uff0c\u8ab0\u8cb7\u5f97\u8d77\uff1f\u300d\u3002 \u5b9a\u50f9\u80cc\u5f8c\u7684\u771f\u76f8\uff1a\u4e26\u975e\u539f\u6599\u6602\u8cb4\uff0c\u800c\u662f\u6280\u8853\u843d\u5f8c \u5927\u773e\u666e\u904d\u5b58\u5728\u4e00\u500b\u8aa4\u89e3\uff0c\u8a8d\u70ba\u80dc\u80bd\u4e4b\u6240\u4ee5\u6602\u8cb4\uff0c\u662f\u56e0\u70ba\u5176\u7d44\u6210\u539f\u6599\uff08\u6c28\u57fa\u9178\uff09\u7a00\u7f3a\u3002\u4e8b\u5be6\u4e0a\uff0c\u6c28\u57fa\u9178\u662f\u5730\u7403\u4e0a\u6700\u8c50\u5bcc\u7684\u6709\u6a5f\u7269\u8cea\u4e4b\u4e00\u3002\u80dc\u80bd\u7684\u5929\u50f9\uff0c\u5b8c\u5168\u662f\u6e90\u65bc\u88fd\u9020\u5de5\u85dd\u7684\u6975\u7aef\u4f4e\u6548\u3002\u9019\u5c31\u662f\u6240\u8b02\u7684\u300c\u5316\u5b78\u66b4\u529b\u300d\u6642\u4ee3\u3002 \u56fa\u76f8\u5408\u6210\uff08SPPS\uff09\u7684\u6280\u8853\u74f6\u9838 \u50b3\u7d71\u7684\u80dc\u80bd\u88fd\u9020\u4e3b\u8981\u4f9d\u8cf4\u65bc 1963 \u5e74\u7531 Bruce Merrifield \u767c\u660e\u7684 \u56fa\u76f8\u80dc\u80bd\u5408\u6210\u6cd5\uff08Solid-Phase Peptide Synthesis, SPPS\uff09\u3002\u96d6\u7136\u9019\u9805\u6280\u8853\u7372\u5f97\u4e86\u8afe\u8c9d\u723e\u734e\u4e26\u958b\u555f\u4e86\u80dc\u80bd\u5316\u5b78\u7684\u5927\u9580\uff0c\u4f46\u5f9e\u5de5\u696d\u751f\u7522\u7684\u89d2\u5ea6\u4f86\u770b\uff0c\u5b83\u672c\u8cea\u4e0a\u662f\u4e00\u7a2e\u300c\u5f37\u884c\u7d44\u88dd\u300d\u7684\u904e\u7a0b\u3002 \u6211\u5011\u53ef\u4ee5\u5c07 SPPS \u5f62\u8c61\u5730\u6bd4\u55bb\u70ba\u300c\u5728\u6c34\u6ce5\u652a\u62cc\u6a5f\u88e1\u7d44\u88dd\u6a02\u9ad8\u300d\uff1a \u96a8\u6a5f\u78b0\u649e\u8207\u5f37\u8feb\u9375\u7d50\uff1a\u5728\u5316\u5b78\u5408\u6210\u4e2d\uff0c\u79d1\u5b78\u5bb6\u5c07\u5927\u91cf\u7684\u6c28\u57fa\u9178\uff08\u6a02\u9ad8\u7a4d\u6728\uff09\u6295\u5165\u53cd\u61c9\u5668\uff0c\u4e26\u52a0\u5165\u9ad8\u6d3b\u6027\u7684\u5076\u5408\u5291\uff08\u81a0\u6c34\uff09\u8207\u6709\u6bd2\u6eb6\u5291\u3002\u70ba\u4e86\u8b93\u5169\u500b\u6c28\u57fa\u9178\u5206\u5b50\u5728\u6b63\u78ba\u7684\u4f4d\u7f6e\u9023\u63a5\uff0c\u5fc5\u9808\u65bd\u52a0\u9ad8\u6eab\u3001\u9ad8\u58d3\uff0c\u4e26\u4f7f\u7528\u904e\u91cf\u7684\u53cd\u61c9\u7269\u4f86\u63a8\u52d5\u5316\u5b78\u5e73\u8861\u3002 \u7acb\u9ad4\u5316\u5b78\u7684\u6df7\u4e82\uff08Racemization\uff09\uff1a\u6c28\u57fa\u9178\u5177\u6709\u638c\u6027\uff08\u5de6\u65cb L-form \u8207 \u53f3\u65cb D-form\uff09\u3002\u5728\u751f\u7269\u9ad4\u5167\uff0c\u9176\u80fd\u7cbe\u78ba\u8b58\u5225\u4e26\u53ea\u4f7f\u7528 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